Aging, exercise, and extracellular matrix in the heart

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Aging, exercise, and extracellular matrix in the heart

Aging is characterized by a progressive impairment of (a) cardiac structure including fibrosis and cardiomyocyte density, and (b) cardiac function including stroke volume, ejection fraction, and cardiac output. The cardiac remodeling involves loss of cardiac myocytes, reactive hypertrophy of the remaining cells, and increased extracellular matrix (ECM) and fibrosis in the aging heart, especiall...

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ژورنال

عنوان ژورنال: Journal of Exercise Rehabilitation

سال: 2013

ISSN: 2288-176X,2288-1778

DOI: 10.12965/jer.130049